| Customization: | Available |
|---|---|
| CAS No.: | 56553-60-7 |
| Formula: | C6h10bnao6 |
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Sodium triacetoxyborohydride is a new type of catalyst for reductive amination. It has excellent universality and selectivity, mild reaction conditions, good catalytic reduction performance, and is easy to separate and purify. The catalyst itself and by-products are non-toxic and have no pollution to the environment. Become the preferred catalyst for reductive amination reactions.
| Product Name | Sodium triacetoxyborohydride |
| CAS No. | 56553-60-7 |
| MF | C6H10BNaO6 |
| EINECS: | 435-580-8 |
| Appearance | powder |
| Packing | 25kg drum |
| Shelf life | 2 Years |
| Melting point | 116-120 °C (dec.) (lit.) |
| Boiling point | 111.1ºC[at 101 325 Pa] |
| density | 1.36[at 20ºC] |
| vapor pressure | 0Pa at 25ºC |
| storage temp. | Inert atmosphere,Room Temperature |
| form | Powder |
| color | White |
| Water Solubility | reacts |
| Item | Standard | Result |
| Appearance | White to off white powder or granule | White powder |
| IR Identification | IR Spectrum should conform with standard | Conforms |
| Assay | More than 97.00% | 98.5% |
1. Sodium Triacetoxyborohydride(STAB) is a hydride reagent used in stereoselective reductive amination. It is able to replace toxic sodium cyanoborohydride under most conditions. It is selective in reducing aldehydes to alcohols in the presence of ketones. STAB is also stable in anhydrous acids, which enables reductive amination of aldehydes and ketones. It used in reductive amination of ketones and aldehydes and reductive amination/lactamization of carbonyl compounds with amines.
2. Reagent for the reductive amination of aryl aldehydes.The advantage of STAB compared to sodium cyanoborohydride is evident.STAB, being non-toxic, is easier to handle and forms no toxic by-products, making the treatment of process waste after the reaction simple and less costly.
3. Selective reducing agent in organic synthesis.
4. Sodium triacetoxyborohydride is especially suitable for reductive aminations. Since the reaction rate for the reduction of iminium ions is much faster than for ketones or even aldehydes, the reductive amination can be carried out as a one-pot procedure by introducing the reducing agent into a mixture of the amine and carbonyl compound. The presence of a stoichiometric amount of acetic acid, which catalyzes the imine formation and provides the iminium ion, doesn't present any problem under these conditions.
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Shandong Baovi Energy Technology Co., LTD.was founded in 2003, and it is a raw material supplier for the global organic chemical industry.The Company also participates in the production of small quantity of high value-added chemicals and intermediates.
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